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Mite tablets are tablets with a minimum dosage and a minimally pronounced effect of a medicinal substance

Seven tablets - tablets with an average dosage and a moderately pronounced effect of the medicinal substance

Oromucosal tablets Buccal (cheek) tablets Lozenge tablets Chewable tablets Sublingual tablets Vaginal tablets Implantable tablets Effervescent tablets Homeopathic tablets Tablets for drops Tablets for paste Tablets for solution Tablets pediatric Tablets for oral use Tablets for oral administration technologies with the aim of releasing a drug or substances in the oral cavity and providing a local or general resorptive effect (cheek pills, sublingual, etc.). Tablets, usually uncoated, which contain medicinal substances intended for absorption through the oral mucosa.

Forte tablets - high dosage tabletsovka and strongly pronounced action of the medicinal substance

Vaginal tablets (compressed vaginal suppositories) are tablets for insertion into the vagina, obtained by pressing a granular powder, which is a processed fatty suppository mass. For better administration, they can have a thin fatty membrane. In addition to vaginal, pressed urethral and rectal dosage forms have also been used. Implantable tablets (depot tablets, implant) are sterile prolonged-release tablets in the form of a very small disk or cylinder for implantation under the skin.

Effervescent tablets - uncoated tablets, usually containing acidic substances and carbonates or bicarbonates, which react quickly in water to release carbon dioxide; they are designed to dissolve or disperse the drug in water immediately before taking it.

Homeopathic tablets - oral tablets obtained by pressing homeopathic triturations, the mass of which in one tablet is, as a rule, from 0.1 to 0.25 g. Tablets for drops - tablets for making drops. Pasta Tablets - Tablets for making pasta. Solution tablets (soluble tablets) - tablets for solution preparation.

The specific route of administration is indicated. Tablets for the preparation of injection solution must be sterile. Pediatric tablets are sweet-taste tablets used in children's practice.

According to the method of preparation, tablets are divided into two types: compressed tablets and trituration tablets. Derivatives of prostaglandins for the treatment of glaucoma Latanoprost Travoprost Bimatoprost Tafluprost.

The composition of Viagra sildenafil (Sildenafil) can be included in a concentration of 25, 50 or 100 mg. In addition to sildenafil, the drug contains: microcrystalline cellulose, calcium hydrophosphate, croscarmellose sodium, magnesium stearate.

Opadry blue and transparent are used for the production of the film coating tablet. The composition of Viagra does not differ depending on the concentration of the active substance.

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The dosage form of Viagra is film-coated tablets. The tablets are slightly biconvex, have a diamond shape, their edges are cut and rounded, the color is blue. On one side of the tablet is the inscription “Pfizer”, on the other - “VGR 25/50/100” (depending on the concentration of sildenafil).

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The action of the drug is aimed at restoring the physiological response to sexual arousal. Viagra is intended for the treatment of erectile dysfunction.

  • Depending on the purpose and method of application, the tablets are divided into the following types
  • When sexual arousal occurs, the agent renews the lower erectile function by increasing blood flow to the penis
  • The natural mechanism of erection is associated with the release of NO (nitric oxide) during sexual stimulation in the cavernous (cavernous) body of the penis, which promotes the activation of the enzyme guanylate cyclase
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The latter, in turn, stimulates an increase in the concentration of cGMP (cyclic guanosine monophosphate). As a result, the smooth muscles of the corpus cavernosum relaxes and blood flow increases.

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Sildenafil is a potent and selective inhibitor of cGMP-specific PDE-5 (phosphodiesterase-5) in the corpus cavernosum, where PDE-5 plays an important role in the breakdown of cGMP.

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The effect of the substance on erectile function is peripheral: the drug does not have a direct relaxing effect on the isolated corpus cavernosum, while powerfully enhancing the relaxing effectno nitrous oxide on it.

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  • To develop the desired therapeutic effect under the influence of sildenafil, sexual arousal is required
  • TCmax (time to reach the maximum plasma concentration) for oral administration of sildenafil on an empty stomach is from 0.5 to 2 hours, the bioavailability indicator is in the range from 25 to 60%

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  • When taking the drug with fatty foods, the pharmacokinetic indicator Cmax decreases by at least 20% (sometimes up to 40%), it takes from 1.5 to 3 hours to reach it
  • Sildenafil metabolization occurs in the liver under the influence of cytochrome microsomal isoenzymes
  • The half-life of sildenafil in its pure form and N-desmethylmetabolite, which is its main metabolite, is from 3 to 5 hours

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  • The drug is excreted as inactive metabolic products
  • About 80% is eliminated with the intestinal contents, about 15% is eliminated by the kidneys
  • Sexual stimulation is essential for the drug to be effective

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  • The drug is prescribed with caution
  • Viagra has a number of contraindications
  • it is forbidden to use the remedy when

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The description of the drug indicates that Viagra is intended for the treatment of erectile dysfunction, which are the result of vascular disorders or nervous disorders and is defined as the inability to achieve an erection of the penis and maintain it for the time required for successful sexual intercourse.

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Also, women, children and adolescents under the age of 18 should not take Viagra. As a rule, the side effects that develop against the background of the use of Viagra are characterized as mild or moderate and are transient. The incidence of unwanted symptoms increases with increasing dosage.

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During clinical studies, side effects such as blurred vision, increased perception of light, rhinitis, dizziness, and vasodilation were also recorded. When using the drug in high doses, the patient has the same side effects, but they occur an order of magnitude more often than if the dosage regimen specified in the instructions is followed.

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In the process of post-marketing use of Viagra in individual patients in connection with the use of the drug, the following were recorded: syncope, arterial hypotension, palpitations, tachycardia; vomit; prolonged erection and / or priapism; redness of the eyes and pain in them; allergic reactions. The instructions for the use of Viagra indicate that the drug should be taken orally. The tablets are recommended to be drunk before meals, since in this case their effect develops more quickly.